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Cardiac Muscle Cell

Heart Muscle Cell

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About the Cardiac Muscle Cell

Heart Muscle Cell

Wall of the heart

Cardiac muscle cells form the heart wall and contract in rhythm without conscious control.

Clinical and real-world context

Heart muscle cells depend on constant oxygen. When blood flow stops they die quickly, which is what happens in a heart attack.

4 structures to explore

  • Intercalated Disc

    The electrical junction

    These stepped junctions lock neighbouring cells together and let electrical signals pass directly, so the heart contracts as one.

    Intercalated discs are found only in cardiac muscle.

  • Myofibrils

    Striped contractile threads

    Like skeletal muscle, cardiac cells contain repeating sarcomeres of actin and myosin, but they are shorter and often branch.

    The heart beats about 100,000 times a day.

  • Mitochondria

    Tireless energy supply

    Cardiac cells are packed with mitochondria because the heart can never rest, and they rely almost entirely on aerobic energy.

    Mitochondria make up around 30 percent of a heart muscle cell's volume.

  • Central Nucleus

    Usually one

    Unlike skeletal fibres, which have many nuclei at the edge, a cardiac cell usually has one nucleus in the middle.

    Adult heart muscle cells divide very rarely.