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Rod Photoreceptor

Light-Sensing Cell

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About the Rod Photoreceptor

Light-Sensing Cell

Back of the eye

Rod cells line the retina and detect very dim light, giving us vision in the dark.

Clinical and real-world context

Loss of rod cells causes night blindness, and is a feature of retinitis pigmentosa.

4 structures to explore

  • Outer Segment

    The stack of light traps

    The outer segment is packed with flat membrane discs full of rhodopsin. A single photon can trigger a signal here.

    New discs form at the base and old ones are shed at the tip and eaten by neighbouring cells every day.

  • Inner Segment

    The powerhouse

    The inner segment is crowded with mitochondria, because maintaining the dark current and rebuilding discs takes a lot of energy.

    Rod cells are among the most energy-hungry cells in the body.

  • Synaptic Terminal

    The hand-off

    At the base, the rod passes its signal on to bipolar neurons by releasing neurotransmitter. Light actually reduces that release.

    In the dark, rods release the most neurotransmitter.

  • Nucleus

    In the nuclear layer

    Rod nuclei line up in a dense band called the outer nuclear layer, easy to spot on retina slides.

    There are about 120 million rod cells in each human eye.